1,2-ジデヒドロ-3β,15-ジメトキシエリトリナン

1,2-ジデヒドロ-3β,15-ジメトキシエリトリナン 化学特性,用途語,生産方法

• 説明

  Cocculus laurifolia yields this alkaloid which occurs primarily in the leaves. The structure has been shown to be that given above based upon chemical and spectroscopic evidence.

• 天然物の起源

  A constituent of the leaves of Cocculus laurifolius D.C., isococculidine is a major component of the alkaloidal extract. It furnishes colourless needles when crystallized from C6H6H6-hexane. The alkaloid is dextrorotatory with a specific rotation of [α]D + 124° (c 1.2, MeOH) and has been shown to possess neuromuscular blocking and hypotensive activities.

• 参考文献

  Bhakuni, Uprety, Widdowson, Phytochem., 15,739 (1976)