こはく酸スマトリプタン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H412：長期的影響により水生生物に有害

• 注意書き

  P202：全ての安全注意を読み理解するまで取り扱わないこ と。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

  P405：施錠して保管すること。

  P501：内容物/容器を．．．に廃棄すること。

こはく酸スマトリプタン 価格

こはく酸スマトリプタン 化学特性,用途語,生産方法

• 外観

  白色～黄赤色～緑色粉末～結晶

• 溶解性

  Soluble to 100 mM in Water and to 75 mM in DMSO

• 効能

  抗片頭痛薬, 血管収縮薬, セロトニン受容体作動薬

• 商品名

  イミグラン (グラクソ・スミスクライン); イミグラン (グラクソ・スミスクライン); イミグラン (グラクソ・スミスクライン)

• 説明

  Sumatriptan succinate is a highly selective 5HT₁-like receptor agonist introduced as a new treatment for migraine. It is indicated for the acute relief of migraine and cluster headache. Oral administration is reported to be free of substantial side effects. The compound appears to be a significant advance over the use of ergotamine and other agents in the treatment of migraine.

• 化学的特性

  White Crystalline Powder

• 使用

  Sumatriptan Succinate is a selective 5-HT1B/1D-receptor agonist with anticonvulsant properties (1,2). Sumatriptan Succinate is used for migraine relief (2).

• 定義

  ChEBI: A succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatm nt of migraine with or without aura in adults.

• 世界保健機関（WHO）

  Suprofen, a nonsteroidal anti-inflammatory agent, was introduced in 1983 for use as an analgesic for the symptomatic relief of mild to moderate pain and for primary dysmenorrhoea. By 1986 it had become evident that its use was occasionally associated with flank pain sometimes accompanied by evidence of decreased renal function. The Arthritis Advisory Committee of the United States Food and Drug Administration met in December 1986 to review the situation and decided against withdrawing suprofen from the market. However, in May 1987 the Committee for Proprietary Medicinal Products of the European Community recommended that all marketing authorizations should be suspended. The manufacturer subsequently decided to suspend sale worldwide on the grounds that sales had diminished to the point where the product was no longer economically viable.

• 生物活性

  Selective 5-HT 1 receptor agonist (K i values are 17, 27 and 100 nM at 5-HT 1D , 5-HT 1B and 5-HT 1A receptors respectively). Antimigraine agent.

こはく酸スマトリプタン 上流と下流の製品情報

こはく酸スマトリプタン 生産企業

Global(442)Suppliers

こはく酸スマトリプタン スペクトルデータ(¹HNMR)

103628-48-4, こはく酸スマトリプタン キーワード