3,6-ジアミノ-10-メチルアクリジニウム・クロリド・塩酸塩

3,6-ジアミノ-10-メチルアクリジニウム・クロリド・塩酸塩 化学特性,用途語,生産方法

• Originator

  Acriflavine hydrochloride,ABCR GmbH and Co. KG

• Manufacturing Process

  4,4-Diaminodiphenylmethane reacted with HNO3 and as a result of this reaction 4,4-diamino-2,2-dinitro-diphenylmethane was obtained. By reducing of 4,4-diamino-2,2-dinitro-diphenylmethane with HCl and Sn, 2,2,4,4-tetraaminodiphenylmethane was produced, which at heating to 150°C gave 3,6-diamino-9,10-dihydroacridine. The 3,6-diamino-9,10-dihydroacridine by oxidation with FeCl3 was converted to 3,6-diaminoacridine. 3,6-Diaminoacridine was reacted with acetanhydride and 3,6-bis- (acetylamino)-acridine was produced. 3,6-Bis-(acetylamino)-acridine was methylated by p-toluolsulfomethyl ether and 3,6-bis-(acetylamino)-10-methylacridinumtosylate was produced. Then the 3,6-bis-(acetylamino)-10-methylacridinumtosylate was converted to 3,6-diamino-10-methylacridinum chloride (acriflavinum chloride) by reaction with hydrochloric acid.

• Therapeutic Function

  Antiseptic, Topical antibacterial

3,6-ジアミノ-10-メチルアクリジニウム・クロリド・塩酸塩 上流と下流の製品情報

6034-59-9, 3,6-ジアミノ-10-メチルアクリジニウム・クロリド・塩酸塩 キーワード