ANTI-CAT IGG, WHOLE MOLECULE FITC CONJUGATED

ANTI-CAT IGG, WHOLE MOLECULE FITC CONJUGATED 化学特性,用途語,生産方法

• 使用

  Anti-Cat IgG (whole molecule)-FITC antibody has been used in immunofluorescence antibody test (IFAT), immunofluorescence.

• 一般的な説明

  IgG?is present in large quantities in the human serum. It constitutes about 10-20% of the plasma proteins.?IgG is composed of glycoproteins, out of which it is 82-96% proteins and 4-18% carbohydrates.?It consists of four sub-classes?i.e?IgG1, IgG2, IgG3, and IgG4. IgG is composed of four polypeptide chains-two heavy chains (γ?chains)?and two light chains (κ or λ?chains)?which are linked by inter-chain?disulfide?bonds.?The heavy chains consist of a N-terminal variable domain (VH) and three constant domains (CH1, CH2, CH3). A hinge region exists between the CH1 and CH2 region. The light chains have one?N-terminal variable domain (VL) and?one?constant domain?(CL). The heavy and the light chains are linked at VH and CH1 domain to form the Fab arm (Fragment antigen binding).?The antigen binds to the V regions of the?antibody.

• Biochem/physiol Actions

  IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.

ANTI-CAT IGG, WHOLE MOLECULE FITC CONJUGATED 生産企業

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