酢酸サルブタモール-(TERT-BUTYL-D9)

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P301+P312：飲み込んだ場合：気分が悪い時は医師に連絡する こと。

  P330：口をすすぐこと。

  P501：内容物/容器を．．．に廃棄すること。

酢酸サルブタモール-(TERT-BUTYL-D9) 価格

酢酸サルブタモール-(TERT-BUTYL-D9) 化学特性,用途語,生産方法

• 説明

  Salbutamol-d₉ is intended for use as an internal standard for the quantification of salbutamol (Item Nos. 21003 | 23991) by GC- or LC-MS. Salbutamol is an agonist of the β₂-adrenergic receptor (β₂-AR; K_d = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). It is selective for β₂-ARs over β₁- and β₃-ARs (K_ds = 46.8 and 21.9 μM, respectively). Salbutamol (25-50 μg/kg, i.v.) reduces acetylcholine-induced bronchospasm in anesthetized guinea pigs. It also reduces response of bronchial muscle to efferent vagal stimulation in anesthetized cats and dogs when administered at doses ranging from 1 to 2.5 and 10 to 20 μg/kg, respectively. Nebulized salbutamol reduces transpulmonary pressure in recurrent airway obstruction-affected horses (EC₅₀ = 39.7 μg). Formulations containing salbutamol have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

• 化学的特性

  Off-White to Pale Yellow Solid

• 使用

  RAC ALBUTEROL-D9 is a labelled β2-adrenoceptor agonist,it is intended for use as an internal standard for the quantification of Albuterol by GC- or LC-mass spectrometry.

酢酸サルブタモール-(TERT-BUTYL-D9) 生産企業

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1173021-73-2, 酢酸サルブタモール-(TERT-BUTYL-D9) キーワード