InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem

InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem 化学特性,用途語,生産方法

• 一般的な説明

  Potent, reversible, and cell-permeable proteasome inhibitor (K_i = 4 nM).Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) which initiates apoptosis. Inhibits NF-κBactivation (IC₅₀ = 3 μM). This material is ≥95% pure by HPLC. A material with ≥98% purity by HPLC (Cat. No. 474791) and the solid form of this compound (Cat. No. 474787) are also available.

• Biochem/physiol Actions

  Cell permeable: yes

InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem 生産企業

Global(2)Suppliers