イソキサフルトール標準品

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H410：長期的影響により水生生物に非常に強い毒性

• 注意書き

  P202：全ての安全注意を読み理解するまで取り扱わないこ と。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

  P391：漏出物を回収すること。

  P405：施錠して保管すること。

イソキサフルトール標準品 価格

イソキサフルトール標準品 化学特性,用途語,生産方法

• 外観

  白色～わずかにうすい黄色、結晶性粉末～粉末

• 溶解性

  水6.2mg/ℓ（pH 5.5、20℃）。アセトン293、ジクロロメタン346、酢酸エチル142、n - ヘキサン0.10、トルエン31.2、メタノール13.8（g/ℓ、20℃）(和光純薬時報 Vol.83, No.2(2015), p23)アセトンに溶け、水及びエタノールにほとんど溶けない。

• 農薬用途

  除草剤

• 説明

  Isoxaflutole is a 4-benzoyl isoxazole molecule and is used as a pre- and early post-emergence herbicide for the control of a wide range of important broadleaf and grass weeds in maize (Zea mays), both in Europe and in North America. It is also registered for use in sugarcane in Central and South America (2–4). It causes characteristic bleaching of newly developed tissues of susceptible species followed by growth cessation and necrosis. Marketed as Balance for corn (maize) in the United States, and Merlin for corn in Europe; and in sugarcane, it mixes well with metolachlor, acetochlor, dimethenamid, and atrazine to complete the weed spectrum and to reduce the application rates of the latter compounds (2). Isoxaflutole also controls triazineresistant weeds in the field (4).

• 使用

  Isoxaflutole is an pesticide used to selectively control both grass and broad-leaved weeds in maize and sugar cane. Isoxaflutole is known to work by inhibiting the enzyme 4-Hydroxyphenylpyruvate dioxygenase (HPPD) which results in the disruption of pigment biosynthesis.

• 作用机制

  4-HPPDを阻害することによってプラストキノンの量が減り，結果的にカロテノイドの生合成が阻害される

• 薬理学

  Isoxaflutole is readily taken up by roots and foliar tissues and then rapidly degraded to a diketonitrile derivative (2-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)- 3-oxo propanenitrile) , which is translocated throughout the plant via xylem and phloem (2,3,6,8). It is this metabolite that inhibits HPPD (7), thereby depleting the plastoquinone pools in developing leaves. Plastoquinone is a cofactor in the desaturation of phytoene, levels of which increase in bleached leaves, concomitant with decreases in colored carotenoids (6). Although bleaching is the primary symptom associated with HPPD inhibition, subsequent growth suppression and necrosis are also believed to be a consequence (8).
  Isoxaflutole also degrades to the diketonitrile derivative in the soil (3,8). The half-life of isoxaflutole in soil is dependent on soil type, pH, and moisture, ranging from 12 hours to 3 days under laboratory conditions (8). The physicochemical properties of isoxaflutole and of diketonitrile play an important role in both soil and herbicidal activity and selectivity (8).

イソキサフルトール標準品 上流と下流の製品情報

イソキサフルトール標準品 生産企業

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