オステオポンチン ヒト

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H290：金属腐食のおそれ

• 注意書き

  P234：他の容器に移し替えないこと。

  P390：物的被害を防止するためにも流出したものを吸収 すること。

オステオポンチン ヒト 価格

オステオポンチン ヒト 化学特性,用途語,生産方法

• 使用

  For research use only. Not for use in diagnostic procedures.
  Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

• 一般的な説明

  The Human OPN ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human OPN in serum, plasma, cell culture supernatants and urine.

• Biochem/physiol Actions

  Osteopontin (OPN) is a secreted glycoprotein and is assumed to be associated with various cellular processes such as adhesion, migration, and biomineralization in diverse tissues. Osteopontin acts as a ligand to αvβ3 integrin and possibly other receptors. In addition to its involvement in mineralized matrix formation, osteopontin can also function as a cytokine that stimulates the release of IFNγ (interferon γ) and IL-12 (interleukin 12), while inhibiting the production of IL-10. Osteopontin is involved in inflammation and also regulates immunity against infectious diseases. It also co-stimulates T cell proliferation. Osteopontin has proinflammatory functions and is associated with multiple sclerosis. It participates in inflammation in Crohn′s Disease. Osteopontin plays a crucial role in bone remodelling and retards ectopic calcification by inhibiting the formation of hydroxyapatite. OPN is thought to prevent renal stone formation by suppressing nucleation, growth and aggregation of calcium oxalate crystals.

オステオポンチン ヒト 生産企業

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