ジフェナジオン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H332：吸入すると有害

  H372：長期にわたる、または反復暴露により臓器の障 害

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P301+P310：飲み込んだ場合：直ちに医師に連絡すること。

  P302+P350：皮膚に付着した場合：多量の水と石鹸で優しく洗うこと。

  P310：ただちに医師に連絡すること。

ジフェナジオン 価格

ジフェナジオン 化学特性,用途語,生産方法

• 外観

  黄色、結晶性粉末～粉末

• 溶解性

  水0.3mg/kg、クロロホルム204、トルエン73、キシレン50、アセトン29、エタノール2.1、ヘプタン1.8（g/ ㎏）(和光純薬時報 Vol.83, No.3(2015), p22)アセトンに溶け、水及びエタノールにほとんど溶けない。

• 効能

  抗凝固薬, ビタミンK拮抗薬

• 説明

  Diphacinone is also called 2-(diphenylacetyl)indan-1,3-dione, is a yellow powder which is practically insoluble in water, readily soluble in chloroform, toluene, xylene, acetone, ethanol, heptane, alkalis [9, p. 431].

• 使用

  Diphacinone is an anticoagulant rodenticide widely used to control rodent infestations.

• 調製方法

  Diphacinone is produced by condensation of 1,1-diphenyl acetone with dimethyl phthalate in the presence of sodium methoxide (30).

• 一般的な説明

  Odorless pale yellow crystals. Used as a rodenticide and anticoagulant medication.

• 空気と水の反応

  Practically insoluble in water (17mg/L). Hydrolyzed by strong acid.

• 反応プロフィール

  DIPHACINONE is a ketone, and behaves as a weak acid. Forms water soluble alkali metal salts. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

• 健康ハザード

  DIPHACINONE is extremely toxic; probable oral lethal dose in humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150-lb. person. Many medical conditions will be aggravated by DIPHACINONE.

• 火災危険

  When heated to decomposition DIPHACINONE emits acrid smoke and fumes. Sensitive to light.

• 作用机制

  ビタミンK依存性の血液凝固因子であるプロトロンビンの生合成を阻害することによって作用を発揮する。

• 农业用途

  Rodenticide: A U.S. EPA restricted Use Pesticide (RUP) when the formulation contains 3% or more of diphacinone. Diphacinone is an anti-coagulant rodenticide bait used for control of rats, mice, voles and other rodents. It is available in meal, pellet, wax block, and liquid bait formulations, as well as in tracking powder and concentrate formulations. It is used in general agriculture and in food-processing areas. The top five uses for diphacinone in California are on landscapes, general vertebrate pest control, around structures and right of ways, and on oranges. This material is also used as an anticoagulant medication. Not approved for use in EU countries.

• 製品名

  DE-PESTER®[C]; DIDANDIN®; DIPAXIN®; DITRAC®; GOLD CREST®; KILL-RO RAT KILLER®; LIQUA-TOX®, diphacinone sodium salt; ORAGULANT®; P. C. Q. ®; PID®; PROMAR®; RAMIK®; RAT KILLER®; RODENT CAKE®[C]; SOLVAN®; TOMCAT®; U 1363®

• 安全性プロファイル

  Poison by ingestion. Inlxbits blood clotting, leading to hemorrhages. Action similar to coumadin (warfarin). A pesticide used in rodent control. When heated to decomposition it emits acrid smoke and irritating fumes

• 代謝経路

  Diphacinone is a member of the indandione class of anti-coagulants. Its fate in rats and mice has been reported but no information on its degradation in soil or plants has been published. It is metabolised by hydroxylation and conjugation.

ジフェナジオン 上流と下流の製品情報

82-66-6, ジフェナジオン キーワード