吉草酸エストラジオール

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H351：発がんのおそれの疑い

  H362：授乳中の子に害を及ぼすおそれ

  H410：長期的影響により水生生物に非常に強い毒性

• 注意書き

  P202：全ての安全注意を読み理解するまで取り扱わないこ と。

  P260：粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。

  P263：妊娠中/授乳期中は接触を避けること。

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P273：環境への放出を避けること。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

吉草酸エストラジオール 価格

吉草酸エストラジオール 化学特性,用途語,生産方法

• 外観

  白色～わずかにうすい黄色, 結晶～粉末

• 溶解性

  エタノール(95)に溶けやすく、水にほとんど溶けない。

• 用途

  卵胞ホルモン剤です。

• 用途

  卵胞ホルモン剤です。

• 効能

  月経障害治療薬, エストロゲン受容体作動薬

• 商品名

  プロギノン (富士製薬工業); ペラニン (持田製薬)

• 説明

  Estradiol valerate (EV), sold for use by mouth under the brand name Progynova and for use by injection under the brand names Delestrogen and Progynon Depot among others, is an estrogen medication. In women, it is used in hormone therapy for menopausal symptoms and low estrogen levels, hormone therapy for transgender women, and in hormonal birth control. It is also used in the treatment of prostate cancer in men. The medication is taken by mouth or by injection into muscle or fat once every 1 to 4 weeks.

• 化学的特性

  White to off-white crystalline powder, odorless. Insoluble in water, easily soluble in ethanol, acetone, chloroform, slightly soluble in vegetable oil.

• 使用

  Estradiol valerate is a female hormone (estrogen). It is used to reduce symptoms of menopause which are vaginal dryness, hot flashes, and others. The symptoms of menopause manifest because the body is making less estrogen; with estradiol valerate, these symptoms are brought to the lowest minimum. This medication therapy can also produce enough estrogen in women with ovarian failure, hypogonadism and can be used by men to treat prostate cancer (palliation only).

• 定義

  ChEBI: Estradiol valerate is a steroid ester. It is the parenterally-administered synthetic valerate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.

• 適応症

  Estradiol valerate is commercially available as an intramuscular injection as the product Delestrogen and is indicated for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only). Estradiol valerate is also available in combination with Dienogest as the commercially available product Natazia used for the prevention of pregnancy and for the treatment of heavy menstrual bleeding.

• 一般的な説明

  Estradiol valerate is a synthetic hormone that is extensively metabolized to estradiol and valeric acid before reaching the systemic circulation. It is well suited for treatment of the characteristic symptoms accompanying menopause in women.

• 副作用

  As with all pharmaceutical medicines, some unwanted effects can occur from the use of estradiol valerate tablets.
  Always consult a physician for medical advice before use.
  Common side effects may include: bloating, vomiting, nausea, breast tenderness, headache, weight changes, and mood changes.
  More severe side effects may include mental changes, breast lumps, vaginal bleeding, liver damage, increased thirst, and sudden vision loss.

• 安全性プロファイル

  Suspected carcinogen with carcinogenic and teratogenic data. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.

吉草酸エストラジオール 上流と下流の製品情報

吉草酸エストラジオール 生産企業

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吉草酸エストラジオール スペクトルデータ(¹HNMR)

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