Anti-Chemokine-like factor superfamily member 4

Anti-Chemokine-like factor superfamily member 4 化学特性,用途語,生産方法

• 使用

  All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
  
  The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

• 一般的な説明

  CKLF (chemokine-like factor) like MARVEL transmembrane domain containing 4 (CMTM4) belongs to the CKLF like MARVEL transmembrane domain containing family (CMTM). The gene is located on human chromosome 16q21-q22.1. It is highly expressed in kidney, heart and brain.

• Biochem/physiol Actions

  CKLF (chemokine-like factor) like MARVEL transmembrane domain containing 4 (CMTM4) functions as a regulator of cell cycle and division in HeLa cells. It acts as a tumor suppressor in clear cell renal cell carcinoma, when downregulated. The protein is involved in cell cycle growth. It regulates the protein programmed death-ligand 1 (PD-L1). It acts a target for microRNA-205 and enhances renal cell apoptosis.

Anti-Chemokine-like factor superfamily member 4 生産企業

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