抗ヒトIGG(FC特異的)抗体 ヤギ宿主抗体

抗ヒトIGG(FC特異的)抗体 ヤギ宿主抗体 化学特性,用途語,生産方法

• 使用

  Anti-Human IgG (Fc specific) antibody produced in goat has been used:
  
  • in double-capture ELISA to measure antiglobulin responses in serum of transplant patients treated with CD52 monoclonal antibodies (CAMPATH-1G)
  • in detection of IgG levels rheumatoid arthritis patients
  • in small intestine biopsies
  • in patients with acute myocardial infarction by immunoblotting

• 一般的な説明

  Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

• Biochem/physiol Actions

  IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.

抗ヒトIGG(FC特異的)抗体 ヤギ宿主抗体 生産企業

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