2-ヒドロキシ-2-メチルプロピオフェノン

化学名:2-ヒドロキシ-2-メチルプロピオフェノン

CAS番号.7473-98-5

英語名:2-Hydroxy-2-methylpropiophenone

CBNumberCB0150675

MFC10H12O2

MW164.2

别名

2-ヒドロキシ-2-メチルプロピオフェノン

1-メチル-1-ベンゾイルエタノール

(1-オキソ-2-ヒドロキシ-2-メチルプロピル)ベンゼン

2-ヒドロキシ-2-メチルプロピオフェノン物理性質

融点	4°C
沸点	102-103 °C4 mm Hg(lit.)
比重(密度)	1.077 g/mL at 25 °C(lit.)
蒸気圧	0.57Pa at 20℃
屈折率	n20/D 1.533(lit.)
闪点	>230 °F
貯蔵温度	Keep in dark place,Sealed in dry,Room Temperature
溶解性	Practically insoluble in water
外見	clear liquid
酸解離定数(Pka)	13.23±0.29(Predicted)
比重	1.077
色	Colorless to Light orange to Yellow
水溶解度	13.3g/L at 20℃
InChIKey	XMLYCEVDHLAQEL-UHFFFAOYSA-N
LogP	1.62 at 25℃
CAS データベース	7473-98-5(CAS DataBase Reference)
EPAの化学物質情報	1-Propanone, 2-hydroxy-2-methyl-1-phenyl- (7473-98-5)

安全性情報

危険有害性情報のコード(GHS)

外観
無色～うすい黄色、液体
定義
本品は、次の化学式で表される有機化合物である。
用途
有機合成原料。
化粧品の成分用途
人工爪剤
化学的特性
Yellowish clear liquid
使用
2-Hydroxy-2-benzoylpropane was used as a catalyst in real-time kinetic study of laser-induced polymerization. It is also a photoinitiator.
一般的な説明
2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.
危険性
Moderately toxic by ingestion.
合成
KBr in water is added to a solution of 2-methyl-1-phenylpropane-1,2-diol in toluene. Then, TEMPO is added. The reddish suspension is cooled to 0°C. A 12 % sodium hypochlorite solution is added while maintaining the internal temperature at 5°C or lower. The mixture is stirred for 1 h at 0-5°C and then separated for 10 min. Sodium dithionite solution (obtained from 30 g sodium dithionite (85%) and 400 ml of water)is added to the organic phase and stirred at 85°C for 1-2 h. The organic phase is again separated and concentrated (rotavap). The crude product is then subjected to fractional distillation, yielding 2-Hydroxy-2-methylpropiophenone as a colorless oil.