N-エチル-3-ヒドロキシ-N,N-ジメチルベンゼンアミニウム

N-エチル-3-ヒドロキシ-N,N-ジメチルベンゼンアミニウム 化学特性,用途語,生産方法

• 用途

  拮抗薬アセチルコリンの分解酵素であるコリンエステラーゼの阻害薬

• 使用

  Antidote (to curare principles); diagnostic aid (myasthenia gravis).

• 定義

  ChEBI: N-Ethyl-N,N-dimethylanilinium in which one of the meta positions is substituted by a hydroxy group. It is a reversible inhibitor of cholinesterase, with a rapid onset (30-60 seconds afte injection) but a short duration of action (5-15 minutes). The chloride salt is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neur muscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.

• brand name

  Enlon (Baxter Healthcare); Reversol (Organon); Tensilon (Valeant).

N-エチル-3-ヒドロキシ-N,N-ジメチルベンゼンアミニウム 生産企業

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