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N-Hydroxy-5-norbornene-2,3-dicarboximide

N-Hydroxy-5-norbornene-2,3-dicarboximide Structure
N-Hydroxy-5-norbornene-2,3-dicarboximide
  • CAS No.21715-90-2
  • Chemical Name:N-Hydroxy-5-norbornene-2,3-dicarboximide
  • CBNumber:CB9121858
  • Molecular Formula:C9H9NO3
  • Formula Weight:179.17
  • MOL File:21715-90-2.mol
N-Hydroxy-5-norbornene-2,3-dicarboximide Property
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36
  • WGK Germany  :3
  • TSCA  :Yes
  • HS Code  :29280090
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a
N-Hydroxy-5-norbornene-2,3-dicarboximide Price More Price(6)
  • Brand: Sigma-Aldrich(India)
  • Product number: 226378
  • Product name : N-Hydroxy-5-norbornene-2,3-dicarboxylic acid imide
  • Purity: 97%
  • Packaging: 50G
  • Price: ₹8075.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H0528
  • Product name : N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis]
  • Purity: 
  • Packaging: 25G
  • Price: ₹3500
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A13205-30
  • Product name : endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97%
  • Purity: 
  • Packaging: 250g
  • Price: ₹19771
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A13205-18
  • Product name : endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97%
  • Purity: 
  • Packaging: 50g
  • Price: ₹6068
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H0528
  • Product name : N-Hydroxy-5-norbornene-2,3-dicarboximide [for Peptide Synthesis]
  • Purity: 
  • Packaging: 250G
  • Price: ₹13800
  • Updated: 2022/05/26
  • Buy: Buy

N-Hydroxy-5-norbornene-2,3-dicarboximide Chemical Properties,Usage,Production

  • Description N-Hydroxy-5-norbornene-2,3-dicarboximide (NHD) is a compound that has antiviral activity and is used to treat HIV infections. It inhibits the reverse transcriptase enzyme in the virus, which blocks the synthesis of viral DNA. The ferroelectric properties of NHD were first observed by observing changes in its melting point when mixed with water. This property makes it useful for diagnosis purposes. In animal studies, a dose of 5 mg/kg was found to be effective against cancer cells and the drug showed no toxicity in humans at doses up to 500 mg/day. The optimal reaction conditions for NHD are pH 6 and temperature 45 degrees Celsius.
  • Chemical Properties white to off-white crystalline powder
  • Uses It decreases racemization in peptide synthesis and inhibits formation of N-acylureas.
  • Uses Inhibits racemization in peptide synthesis using DCC as condensing agent.
  • Uses N-Hydroxy-5-norbornene-2,3-dicarboximide(HONB) is used in solution-phase peptide synthesis. Used in the synthesis of enkephalin analogs.
  • Purification Methods Dissolve the imide in CHCl3, filter, evaporate and recrystallise from EtOAc. IR (nujol): max 1695, 1710 and 1770 (C=O), and 3100 (OH) cm-1. The O-acetyl derivative has m 113-114o (from EtOH) with IR bands at max 1730, 1770 and 1815 cm-1 only, and the O-benzoyl derivative has m 143-144o (from propan-2-ol or *C6H6). [Bauer & Miarka J Org Chem 24 1293 1959, Fujino et al. Chem Pharm Bull Jpn 22 1857 1974]. [Beilstein 21/10 V 188.]
N-Hydroxy-5-norbornene-2,3-dicarboximide Preparation Products And Raw materials
Raw materials
Preparation Products
N-Hydroxy-5-norbornene-2,3-dicarboximide Suppliers
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N-Hydroxy-5-norbornene-2,3-dicarboximide Spectrum
21715-90-2, N-Hydroxy-5-norbornene-2,3-dicarboximideRelated Search:
  • Synthetic Organic Chemistry
  • Peptide Synthesis
  • Coupling Reactions (Peptide Synthesis)
  • Condensation & Active Esterification
  • Biochemistry
  • Medical Intermediates
  • Coupling Reagent
  • 抑制剂
  • 医药化工原料
  • 高端化学
  • 原料药
  • 化工原料
  • 有机化工原料
  • 生化试剂-其他化学试剂
  • 缩合剂
  • 医药中间体
  • 肽键缩合剂
  • 中间体
  • 缩合试剂
  • 化学生物学
  • 氮化合物
  • 化学试剂
  • 多肽耦合
  • Active Esters/Additives
  • Condensation & Active Esterification
  • Peptide Synthesis
  • Coupling Reactions (Peptide Synthesis)
  • Coupling
  • Synthetic Reagents
  • 5C9H9NO3
  • 化合物 HONB
  • N-羟基-5-降冰片烯-2,3-二羰基亚胺 (HONB)
  • N-羟基-5-降冰片烯-2,3-酰亚胺
  • N-羟基-5-降冰片稀-2,3-二酰亚胺
  • 内型-N-羟基-5-降冰片烯-2,3-二甲酰亚胺
  • HONB(N-羟基-5-降冰片烯-2,3-二羧酰亚胺)
  • N-羟基-5-降冰片烯-2,3-二酰亚胺
  • N-羟基-5-降冰片烯-2,3-二羰酰亚胺
  • N-羟基-5-降冰片烯-2,3-二羧酸酰亚胺
  • N-羟基-5-降冰片烯-2,3-二甲酰亚胺
  • N-羟基-5-降冰片烯-2,3-二甲酰亚胺[用于肽合成](HONB)
  • HONB N-羟基-5-降冰片烯-2,3-二甲酰亚胺
  • N-羟基双环[2.2.1]-5-庚烯-2,3-二甲酰亚胺
  • N-羟基-5-降冰片稀-2,3-二酰亚胺(HONB)
  • 内-N-羟基-5-降冰片烯-2,3-二甲酰亚胺,97%
  • N-羟基-5-降冰片烯-2,3-二甲酰亚胺[用于肽合成]
  • HONBN-羟基-5-降冰片稀-2,3-二酰亚胺
  • 内-N-羟基-5-降冰片烯-2,3-二甲酰亚胺
  • N-羟基5-降冰片烯-2,3-二羟基亚胺
  • 21715-90-2
  • <i>N</i>-Hydroxy-5-norbornene-2,3-dicarboxylic acid imide
  • N-Hydroxy-5-Norbornene-2,3-dimethylimide
  • 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-Methanoisoindole-1,3(2H)-dione
  • HONB
  • N-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ACID IMIDE
  • N-Hydroxy-5-norbornene-2,3-dicarboximide[forPeptideSynthesis]&gt
  • N-hydroxy-5-norbornene-2.3-dicarboxylimide(HONB)
  • N-Hydroxy-5-norbornene-2,4-dicarboximide

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