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3-(Trifluoromethyl)cinnamic acid

3-(Trifluoromethyl)cinnamic acid Structure
3-(Trifluoromethyl)cinnamic acid
  • CAS No.779-89-5
  • Chemical Name:3-(Trifluoromethyl)cinnamic acid
  • CBNumber:CB8295905
  • Molecular Formula:C10H7F3O2
  • Formula Weight:216.16
  • MOL File:779-89-5.mol
3-(Trifluoromethyl)cinnamic acid Property
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38-37/38
  • Safety Statements  :26-37/39-37
  • WGK Germany  :3
  • TSCA  :Yes
  • HazardClass  :IRRITANT
  • HS Code  :29163990
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P302+P352-P305+P351+P338
3-(Trifluoromethyl)cinnamic acid Price More Price(4)
  • Brand: TCI Chemicals (India)
  • Product number: T1547
  • Product name : 3-(Trifluoromethyl)cinnamic Acid
  • Purity: min. 99.0 %
  • Packaging: 5G
  • Price: ₹2900
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A16983-14
  • Product name : 3-(Trifluoromethyl)cinnamic acid, predominantly trans, 98+%
  • Purity: 
  • Packaging: 25g
  • Price: ₹7990
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: T1547
  • Product name : 3-(Trifluoromethyl)cinnamic Acid
  • Purity: min. 99.0 %
  • Packaging: 25G
  • Price: ₹11800
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-A16983-06
  • Product name : 3-(Trifluoromethyl)cinnamic acid, predominantly trans, 98+%
  • Purity: 
  • Packaging: 5g
  • Price: ₹2340
  • Updated: 2022/05/26
  • Buy: Buy

3-(Trifluoromethyl)cinnamic acid Chemical Properties,Usage,Production

  • Chemical Properties White Solid
  • Uses 3-(Trifluoromethyl)cinnamic acid is used in the synthesis of cinacalcet. Cinacalcet is a drug for the control and treatment of secondary hyperparathyroidism (in the dialysis population), primary hyperparathyroidism where the patient may not be a candidate for surgical treatment, and for the treatment of calciphylaxis in patients with end-stage renal disease or in patients on dialysis.
  • Uses Had sedative hypnotic activity in mice, showing potent inhibition of spontaneous motility.
  • Definition ChEBI: (E)-3-(trifluoromethyl)cinnamic acid is a member of the class of (trifluoromethyl)benzenes consisting of trans-cinnamic acid having a trifluoromethyl substituent at the meta-position. It is a member of cinnamic acids, a member of styrenes and a member of (trifluoromethyl)benzenes. It is functionally related to a trans-cinnamic acid.
  • Synthesis To a suspension of m-trifluoromethyl-α-bromohydrocinnamic acid, isopropanol (1.42 1) and benzyltriethylammonium chloride (10.85g), aqueous sodium hydroxide (340 ml, 56%) was added slowly. The temperature was raised to 55-60℃, stirred for 7 hours, and isopropanol was removed in vacuo. Water (500ml) was added to the reaction mass, stirred, cooled to 0℃, and acidified with hydrochloric acid (450ml). The solid was filtered, washed with water, and dried in vacuo at 5O℃ to afford 204g of 3-(Trifluoromethyl)cinnamic acid.
    3-(Trifluoromethyl)cinnamic acid
3-(Trifluoromethyl)cinnamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-(Trifluoromethyl)cinnamic acid Suppliers
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  • Country：China
  • ProdList：21628
  • Advantage：55
3-(Trifluoromethyl)cinnamic acid Spectrum
779-89-5, 3-(Trifluoromethyl)cinnamic acidRelated Search:
  • 11
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