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Esculin

Description References

Esculin

CAS No.531-75-9
Chemical Name:Esculin
CBNumber:CB8245061
Molecular Formula:C15H16O9
Formula Weight:340.28
MOL File:531-75-9.mol

Esculin Property

Melting point 203 °C
alpha -88 º (c=2,dioxane/water1:1)
Boiling point 396.1°C (rough estimate)
Density 0.791 g/mL at 20 °C
vapor pressure 0Pa at 25℃
refractive index -79 ° (C=2.4, 50% Dioxane)
Flash point 15 °C
storage temp. 2-8°C
solubility methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
form Liquid
pka 7.00±0.20(Predicted)
color Clear
optical activity [α]20/D 41±2°, c = 5% in pyridine
Water Solubility MODERATELY SOLUBLE
Merck 3698
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey YRABYCJKUBFWQY-FHXAZYNBSA-N
LogP -1.307 (est)
CAS DataBase Reference 531-75-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1Y1L18LQAF
NIST Chemistry Reference 7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
EPA Substance Registry System Esculin (531-75-9)
UNSPSC Code 85151701
NACRES NA.83

Safety

Hazard Codes :F,C,Xi
Risk Statements :11-20/21/22-34-68/20/21/22-36/37/38
Safety Statements :26-36/37/39-45-24/25-36/37-16
RIDADR :UN 2924 3/PG 2
WGK Germany :3
RTECS :DJ3085000
F :3-10-23
HS Code :29389090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302
Precautionary statements P264-P270-P301+P312+P330-P501

Esculin Price More Price(12)

Brand: Sigma-Aldrich(India)
Product number: E8250
Product name : Esculin hydrate
Purity: ≥98%
Packaging: 5G
Price: ₹4145.98
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: E8250
Product name : Esculin hydrate
Purity: ≥98%
Packaging: 25G
Price: ₹10727.58
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: E8250
Product name : Esculin hydrate
Purity: ≥98%
Packaging: 100G
Price: ₹31132.7
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich
Product number: 06212
Product name : Esculin hydrate
Purity: analytical standard
Packaging: 100MG
Price: ₹6170.25
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 06212
Product name : Esculin hydrate
Purity: analytical standard
Packaging: 100MG
Price: ₹6170.25
Updated: 2022/06/14
Buy: Buy

Esculin Chemical Properties,Usage,Production

Description Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.
References [1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011
Chemical Properties White to nearly white
Uses Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.
Uses esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.
Uses esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.
Definition ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.
General Description Esculin hydrate has vasoprotective and venotonic properties.
Flammability and Explosibility Not classified
Biochem/physiol Actions Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).