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3-Furoic acid

CAS No.488-93-7
Chemical Name:3-Furoic acid
CBNumber:CB5473553
Molecular Formula:C5H4O3
Formula Weight:112.08
MOL File:488-93-7.mol

3-Furoic acid Property

Melting point 120-122 °C (lit.)
Boiling point 229.64°C
Density 1.3220
refractive index 1.4710 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.9(at 25℃)
color Off-White to Beige
Water Solubility insoluble
BRN 108638
InChIKey IHCCAYCGZOLTEU-UHFFFAOYSA-N
LogP 1.030
CAS DataBase Reference 488-93-7(CAS DataBase Reference)
FDA UNII 88A3S7RG98
NIST Chemistry Reference 3-Furancarboxylic acid(488-93-7)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xi,C
Risk Statements :36/37/38-34
Safety Statements :26-36/37-45-36/37/39-36
WGK Germany :3
HazardClass :IRRITANT
HS Code :29321900

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319
Precautionary statements P302+P352-P305+P351+P338

3-Furoic acid Price More Price(10)

Brand: Sigma-Aldrich(India)
Product number: 163392
Product name : 3-Furoic acid
Purity: 98%
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Brand: Sigma-Aldrich(India)
Product number: 163392
Product name : 3-Furoic acid
Purity: 98%
Packaging: 25G
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Brand: TCI Chemicals (India)
Product number: F0304
Product name : 3-Furancarboxylic Acid
Purity:
Packaging: 5G
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Brand: ALFA India
Product number: ALF-L11629-14
Product name : 3-Furoic acid, 99%
Purity:
Packaging: 25g
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Brand: TCI Chemicals (India)
Product number: F0304
Product name : 3-Furancarboxylic Acid
Purity:
Packaging: 25G
Price: ₹12200
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3-Furoic acid Chemical Properties,Usage,Production

Description 3-Furoic acid, also known as 3-carboxyfuran or 3-furoate, belongs to the class of organic compounds known as furoic acids. These are organic compounds containing a furoic acid moiety, with a structure characterized by a furan ring bearing a carboxylic acid group at the C2 or C3 carbon atom.
3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals. It is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Chemical Properties white to light yellow crystal powde
Uses 3-Furoic acid can be used as a reactant to synthesize:
- Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
- (±)-Hyperolactone A by reacting with 2-methylbutanal.
- Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.
Uses 3-Furoic acid can be used as a reactant to synthesize:
Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
(±)-Hyperolactone A by reacting with 2-methylbutanal.
Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.
Uses 3-Furoic acid is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Definition ChEBI: A furoic acid carrying the carboxy group at position 3.
Synthesis Reference(s) Tetrahedron Letters, 26, p. 1509, 1985 DOI: 10.1016/S0040-4039(00)98538-1
Biological Activity 3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Biochem/physiol Actions 3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Purification Methods Crystallise the acid from water or aqueous EtOH, and sublime it in a vacuum. [Beilstein 18 I 439, 18 III/IV 4052, 18/6 V 196.]