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N-(tert-Butoxycarbonyl)-L-phenylalanine

N-(tert-Butoxycarbonyl)-L-phenylalanine Structure
N-(tert-Butoxycarbonyl)-L-phenylalanine
  • CAS No.13734-34-4
  • Chemical Name:N-(tert-Butoxycarbonyl)-L-phenylalanine
  • CBNumber:CB4781305
  • Molecular Formula:C14H19NO4
  • Formula Weight:265.3
  • MOL File:13734-34-4.mol
N-(tert-Butoxycarbonyl)-L-phenylalanine Property
  • Melting point 85-87 °C(lit.)
  • Boiling point 408.52°C (rough estimate)
  • Density 1.1356 (rough estimate)
  • refractive index 24.5 ° (C=1, EtOH)
  • storage temp. Keep in dark place,Sealed in dry,Room Temperature
  • solubility Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone.
  • form Fine Crystalline Powder
  • pka 3.88±0.10(Predicted)
  • color White
  • optical activity [α]20/D +25±1°, c = 1% in ethanol
  • BRN 2219729
  • CAS DataBase Reference 13734-34-4(CAS DataBase Reference)
  • EPA Substance Registry System L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4)
  • UNSPSC Code 12352209
  • NACRES NA.22
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P280-P271
N-(tert-Butoxycarbonyl)-L-phenylalanine Price More Price(17)
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.53006
  • Product name : Boc-Phe-OH
  • Purity: Novabiochem?
  • Packaging: 25G
  • Price: ₹3080.01
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.53006
  • Product name : Boc-Phe-OH
  • Purity: Novabiochem?
  • Packaging: 100G
  • Price: ₹6280
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.53006
  • Product name : Boc-Phe-OH
  • Purity: Novabiochem?
  • Packaging: 8530061000
  • Price: ₹84990
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 15480
  • Product name : Boc-Phe-OH
  • Purity: ≥99.0% (T)
  • Packaging: 5G
  • Price: ₹2543.88
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 15480
  • Product name : Boc-Phe-OH
  • Purity: ≥99.0% (T)
  • Packaging: 25G
  • Price: ₹6516.65
  • Updated: 2022/06/14
  • Buy: Buy

N-(tert-Butoxycarbonyl)-L-phenylalanine Chemical Properties,Usage,Production

  • Chemical Properties N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder
  • Uses N-Boc-L-phenylalanine is a derivative of Phenylalanine used in enantioselective hydrolysis of amino acid esters.
  • Uses N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.
  • Preparation Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).
  • reaction suitability reaction type: Boc solid-phase peptide synthesis
    reaction type: C-H Activation
    reagent type: ligand
    reaction type: Peptide Synthesis
N-(tert-Butoxycarbonyl)-L-phenylalanine Preparation Products And Raw materials
Raw materials
Preparation Products
N-(tert-Butoxycarbonyl)-L-phenylalanine Suppliers
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N-(tert-Butoxycarbonyl)-L-phenylalanine Spectrum
13734-34-4, N-(tert-Butoxycarbonyl)-L-phenylalanineRelated Search:
  • 1
  • Inhibitors
  • Aromatics
  • Amino Acids & Derivatives
  • Boc-Amino acid series
  • Boc-Amino Acids
  • Biochemistry
  • Amino Acids (N-Protected)
  • Protected Amino Acids
  • AMINOACIDS DERIVATIVES
  • Amino Acids
  • Boc-Amino Acids and Derivative
  • Phenylalanine [Phe, F]
  • 生物化工
  • 化学品
  • 抑制剂
  • 化工原料及中间体
  • 系列1
  • 保护氨基酸-苯丙氨酸(Phe)
  • 对照品
  • 其他中间体材料
  • 保护氨基酸系列-BOC-氨基酸
  • 医药及有机合成中间体
  • 化学试剂
  • 保护氨基酸系列-BOC类保护氨基酸
  • 通用生化试剂-氨基酸
  • 无机物
  • 化工
  • 有机化工原料
  • 化工中间体
  • 化工原料
  • 化工中间体工业原料
  • 生化试剂-氨基酸
  • 原料
  • 有机原料
  • 化学试剂
  • 中药对照品
  • 生化试剂-氨基酸类
  • 氨基酸和衍生物
  • 胺基酸
  • 氨基酸及其衍生物
  • 有机硅化合物,氟化学
  • 医药原料
  • 氨基酸类
  • 保护氨基酸
  • Boc-保护氨基酸
  • 其他生化试剂
  • 氨基酸衍生物
  • 中间体
  • 化学生物学
  • 医药中间体
  • 生物化学品
  • 生化试剂
  • 氨基酸
  • Amino Acid Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • Phenylalanine

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