Uses
anticonvulsant, analgesic, anxiolytic, suppreses excitatory postsynaptic potential
Uses
rac-Kavain is the main kavalactone found in the roots of the kava plant. Kavain is known to exhibit anticonvulsive properties by attenuating vascular smooth muscle contraction through interactions with voltage-dependent sodium and calcium channels. rac-Kavain was shown in recent research to exhibit protective properties on anaerobic glycolysis, ATP content and intracellular calcium and sodium of anoxic brain vesicles.
Definition
ChEBI: DL-kavain is https://www.chemicalbook.com/ProductChemicalPropertiesCB9738874_EN.htm It has a role as a glycine receptor antagonist.
Synthesis Reference(s)
The Journal of Organic Chemistry, 41, p. 4070, 1976
DOI: 10.1021/jo00888a004
