Description
L-phenylglycine (Cephalexin EP Impurity A) is a derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in the spinal cord and an allosteric modulator of NMDA receptors.
Storage
Store at room temperature. Store in cool dry place in tightly closed container. Store away from oxidizing agent.
Description
d-Phenylglycine is widely used in large
quantity as the side chain that makes ampicillin
and cephalexin orally acceptable.
Chemical Properties
White crystalline powder
Uses
D-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Uses
D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r
eceptors.
Definition
ChEBI: The R stereoisomer of alpha-phenylglycine.
Flammability and Explosibility
Non flammable
Synthesis
Industrially, dphenylglycine
has been produced by a conventional
resolution method or by kinetic resolution
with acylase. Another enzymatic procedure has
been developed by Yamada et al. ,
as shown below.
