Description
Isoprocarb, o-cumenyl methylcarbamate
(IUPAC), consists of colorless crystals, which are sparingly soluble in water and are readily soluble in acetone and methanol.
Isoprocarb is produced by reaction of 2-isopropylphenol
with methylisocyanate. Isoprocarb is used for control of
rice, cacao, sugarcane, and vegetable pests.
Chemical Properties
Isoprocarb is a carbamate insecticide. It is a colourless crystalline substance, sparingly soluble in water (0.265g/l) and readily soluble in acetone(400g/l) and methanol (125g/l). It is hydrolysed in alkaline media.
The insecticide,with contact and stomach action, effectively controls leafhoppers,plant hoppers and aphids on a variety of crops like rice, cocoa, sugarcane and vegetables. Its residual activity gives effective pest control. It acts by inhibiting cholinesterase.
Uses
Isoprocarb is a non-systematic carbamate insecticide. Isoprocarb functions by reversibly inactivating the enzyme acetylcholinesterase in insects.
Definition
ChEBI: Isoprocarb is a carbamate ester. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a carbamate insecticide and an agrochemical. It is functionally related to a methylcarbamic acid and a 2-isopropylphenol.
Toxicology
The insecticide isoprocarb is a Class II toxin (moderately hazardous), with the acute oral LD50 among rats being 403-485mg/kg, while the percutaneous LD50 among male rats and mice is>500mg. It is a PAN Bad Actor chemical, since it is a cholinesterase inhibitor. Symptoms of poisoning with this insecticide include muscle weakness,dizziness,salivation,nausea,vomiting,sweating,headache,effects on the CNS and depression. PPE such as splash-resistant safety goggles and chemicalresistant clothing, gloves and masks are advised.
Safety Profile
Poison by ingestion,
intravenous, and intraperitoneal routes.
Moderately toxic by skin contact. When
heated to decomposition it emits toxic
fumes of NOx. See also CARBAMATES.
Used for controlling leafhoppers,
planthoppers, and bugs in rice and cacao.
