ANTI-SEROTONIN RECEPTOR (5-HT2BR)

General Description

Multiplbe genes encode different subtypes of serotonin (5HT) receptor and are species specific. HTR2B is expressed in mammalian brain and is localized to GABA (γ-aminobutyric acid) producing neurons of dorsal hypothalamic nucleus. The HTR2B gene is mapped to human chromosome 2q37.1.

Biochem/physiol Actions

The functions of serotonin (5HT) receptors are associated with sleep disorders, anxiety, depression and schizophrenia.