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Pranoprofen

Pranoprofen Structure
Pranoprofen
  • CAS No.52549-17-4
  • Chemical Name:Pranoprofen
  • CBNumber:CB9189564
  • Molecular Formula:C15H13NO3
  • Formula Weight:255.27
  • MOL File:52549-17-4.mol
Pranoprofen Property
  • Melting point: :182-183°
  • Boiling point: :398.5°C (rough estimate)
  • Density  :1.1654 (rough estimate)
  • refractive index  :1.5500 (estimate)
  • storage temp.  :2-8°C
  • pka :4.27±0.10(Predicted)
  • form  :powder
  • color  :white to beige
  • CAS DataBase Reference :52549-17-4(CAS DataBase Reference)
  • FDA UNII :2R7O1ET613
Safety
  • RIDADR  :UN 2811 6.1 / PGIII
  • RTECS  :DJ3100950
  • Toxicity :LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Pranoprofen Price More Price(6)
  • Brand: Sigma-Aldrich
  • Product number: SML1423
  • Product name : Pranoprofen
  • Purity: ≥98% (HPLC)
  • Packaging: 50mg
  • Price: $31.3
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: SML1423
  • Product name : Pranoprofen
  • Purity: ≥98% (HPLC)
  • Packaging: 250mg
  • Price: $116
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 17875
  • Product name : Pranoprofen
  • Purity: ≥98%
  • Packaging: 1g
  • Price: $295
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 17875
  • Product name : Pranoprofen
  • Purity: ≥98%
  • Packaging: 50mg
  • Price: $25
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 17875
  • Product name : Pranoprofen
  • Purity: ≥98%
  • Packaging: 100mg
  • Price: $48
  • Updated: 2020/06/24
  • Buy: Buy

Pranoprofen Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Originator Niflan, Yoshitomi ,Japan ,1981
  • Uses Pranoprofen is an anti-inflammatory used in ophthalmology.
  • Manufacturing Process A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
  • Therapeutic Function Analgesic, Antiinflammatory
Pranoprofen Preparation Products And Raw materials
Raw materials
Preparation Products
Global(187)Suppliers
  • Supplier:
    Henan Tianfu Chemical Co.,Ltd.
  • Tel:0371-55170693
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  • Supplier:
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  • Fax:
  • Email:marketing@targetmol.com
  • Country:United States
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  • Advantage:58
52549-17-4, PranoprofenRelated Search:
  • PRANOPROFEN
  • (RS)-Pranoprofen
  • 5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, a-methyl- (9CI)
  • a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid
  • dl-Pranoprofen
  • Niflan
  • Y 8004
  • pyranoprofen
  • (S)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • [S,(+)]-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • (R)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • [R,(-)]-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
  • Cesflan
  • α-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid
  • 2-(5h-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic acid
  • Oftalar
  • Pranoprofen, >=99%
  • 5H-[1]Benzopyrano[2,3-b]pyridine-7-aceticacid, a-methyl-
  • Pranoprofen-13C-d3
  • Pranoprofen(mixture of isomers)
  • 52549-17-4
  • NIFLAN
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • >97%,BR