Biological Activity
Citramalate is a biochemical intermediate known to be involved in several aspects of bacterial metabolism, including, among others, the anaerobic metabolism of glutamate via the methylaspartate pathway of Clostridium tetanomorphum.
References
[1] D M HOWELL R H W H Xu. (R)-citramalate synthase in methanogenic archaea.[J]. Journal of Bacteriology, 1999, 181 1: 331-333. DOI:
10.1128/jb.181.1.331-333.1999[2] W BUCKEL H A B. Two pathways of glutamate fermentation by anaerobic bacteria.[J]. Journal of Bacteriology, 1974, 117 3: 1248-1260. DOI:
10.1128/jb.117.3.1248-1260.1974[3] SILKE FRIEDMANN Georg F Birgit E Alber. Properties of succinyl-coenzyme A:D-citramalate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.[J]. Journal of Bacteriology, 2006, 188 18: 6460-6468. DOI:
10.1128/jb.00659-06
