Description
This simple piperidine base has recently been discovered in the oxygenated
fraction from Piper nigrum. The structure has been elucidated from chemical
and spectroscopic data.
Chemical Properties
CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID
Uses
Reactant for:
- Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate
- Vilsmeier-type reactions of pyrazoles with amides in the presence of phosphorous oxychloride
- CO-free aminocarbonylation of N-substituted formamides with aryl iodides/bromides catalyzed by palladium acetate and Xantphos for synthesis of arylamides
- Synthesis of alternating copolymers for organic photovoltaic applications
- One-pot double functionalization of π-deficient heterocyclic lithium reagents
- Synthesis of thermally stable piezofluorochromic aggregation-induced emission compounds
Uses
Solvent for polar and nonpolar compounds, as well as many high polymers; gas absorption; plastics modifiers.
Definition
ChEBI: 1-Piperidinecarboxaldehyde is a member of piperidines.
References
Debrauwere, Verzale, Bull. Soc. Chim. Belg., 84, 167 (1975)