Lithospermic acid (50 mg/kg, po for 6 days) exhibits cardioprotective efficacy against MI/R injury in mouse models[2].
Lithospermic acid (10-30 mg/kg, po, single dose) exhibits uric acid lowering and anti-inflammatory effects in rats hyperuricemia and gouty arthritis models[3].
| Animal Model: | C57BL/6 mouse MI/R injury models[2] |
| Dosage: | 50 mg/kg |
| Administration: | po for 6 days |
| Result: | Improved MI/R-induced cardiac dysfunction. |
| Animal Model: | Hyperuricemia and gouty arthritis model[3] |
| Dosage: | 10-30 mg/kg |
| Administration: | po, single dose |
| Result: | Reduced the serum uric acid and monosodium urate crystal-induced paw edema. |
