SU 6668
- Product NameSU 6668
- CAS210644-62-5
- CBNumberCB91312244
- MFC18H18N2O3
- MW310.35
- MDL NumberMFCD09743433
- MOL File210644-62-5.mol
Chemical Properties
| storage temp. | +2C to +8C |
| solubility | DMSO : 50 mg/mL (161.11 mM; Need ultrasonic) |
| form | Dark yellow solid |
| NCI Dictionary of Cancer Terms | SU6668 |
SU 6668 Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Sigma-Aldrich CDS023028 | 100MG | $308 | 2,4-Dimethyl-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-pyrrole-3-propanoic acid |
Buy |
| Tocris 3335 | 10 | $208 | SU6668 ≥99%(HPLC) |
Buy |
| TRC D457088 | 5mg | $90 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid(SU-6668) |
Buy |
| Usbiological 256776 | 10mg | $466 | SU 6668 |
Buy |
| Matrix Scientific 132613 | 250mg | $537 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 97% |
Buy |
SU 6668 Chemical Properties,Usage,Production
Uses
PDGFR Tyrosine Kinase Inhibitor VI, SU6668 is a potent ATP-competitive inhibitor against tyrosine kinases.General Description
A cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC50 = 0.01, 0.1, 3.9, and 3.8 μM, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development in vivo. Although initially characterized as an RTK inhibitor, SU6668 is now also known to target ser/thr kinases Aurora A, Aurora B, TBK1 (NAK/T2K), and AMPK (IC50 = 0.85, 0.047, 1.4, and 1.8 μM, respectively), as well as non-receptor TKs Lyn and Yes (IC50 = 4.3 and 5.8 μM, respectively).Preparation Products And Raw materials
SU 6668 Supplier
Global(49)Suppliers
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| +8615604608665 15604608665 |
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| 13951936332 18305166317 |
info@serpharm.com | China | 494 | 55 |
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