Chemical Properties
Off white powder
Uses
Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor[1][2].
Definition
ChEBI: A flavanone glycoside that is eriodictyol substituted by a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.
Biological Activity
Neoeriocitrin was one of several flavonoids th at completely blocked the okadaic acid-induced inhibition of autophagy in cultured mouse hepatocytes. It is suggested as tool in the study of intracellular protein phosphorylation and as a potential protectant against pathological hyperphosphorylations.
References
[1] Li L, et al. Comparison of?neoeriocitrin?and naringin on proliferation and osteogenic differentiation in MC3T3-E1. Phytomedicine.?2011 Aug 15;18(11):985-9. DOI:
10.1016/j.phymed.2011.03.002[2] Liu C, et al. Extraction and Isolation of Acetylcholinesterase Inhibitors from Citrus limon Peel Using an in vitro Method. J Sep Sci.?2020 Jan 30. DOI:
10.1002/jssc.201901252
