Uses
12:0 DG has been used as an internal standard for spiking serum samples for liquid chromatography–mass spectrometry?analysis. It may be used as an internal standard for spiking RAW 264.7 cells for mass spectroscopy studies and in reverse phase liquid chromatography coupled mass spectrometer for lipidomics studies of human plasma and serum samples.
Definition
ChEBI: 1,2-dilauroyl-sn-glycerol is a 1,2-diglyceride.
General Description
sn-1,2-diacylglycerols comprise short saturated acyl side chains (C4-C10) and 12:0 DG is also called 1,2-dilauroyl-
sn-glycerol.
Biochem/physiol Actions
1,2-dilauroyl-sn-glycerol is a polymerization initiator used in the synthesis of (R)-3-((2-bromo-2-methylpropanoyl)oxy)propane-1,2-diyl didodecanoate (BMPD). sn-1,2-diacylglycerols are prime regulators of biological functions especially in platelets. They also activate protein kinase C.
