Chemical Properties
White powder
Uses
Basic building block for synthesizing azetidines.1,2
Uses
Azetidine hydrochloride is a building block for azetidine synthesis and a pharmaceutical intermediate.
Uses
Azetidine hydrochloride is a four-membered ring nitrogen-containing heterocycle. Useful building block in the synthesis of polypeptides and other nitrogen containing compounds with potential biological properties.
General Description
Azetidine derivatives are an essential class of aza-heterocyclic compounds with various biological activities and have been widely used as building blocks in pharmacological research. Although azetidine has the simplest structure, it is only commercially available in small quantities and at a high price. In addition, this compound is hard to synthesize for several reasons, such as cyclization of the four-membered ring, stability of the ring, and low boiling point[1].
References
[1] Jian Sun, Qi Sun, S. Gong. “A Novel Strategy for the Synthesis of Azetidine.” Advanced Materials Research 6 1 (2013): 135–138.