Uses and Synthetic Methods of Amygdalin Category Toxicity classification Acute toxicity Flammability Hazardous properties Storage and transportation Fire extinguishing agent
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Amygdalin

Uses and Synthetic Methods of Amygdalin Category Toxicity classification Acute toxicity Flammability Hazardous properties Storage and transportation Fire extinguishing agent
Amygdalin Structure
Amygdalin
  • CAS No.29883-15-6
  • Chemical Name:Amygdalin
  • CBNumber:CB8363552
  • Molecular Formula:C20H27NO11
  • Formula Weight:457.43
  • MOL File:29883-15-6.mol
Amygdalin Property
  • Melting point: :223-226 °C
  • Boiling point: :563.27°C (rough estimate)
  • alpha  :-38.5 º (c=4, H2O)
  • Density  :1.4474 (rough estimate)
  • refractive index  :-40 ° (C=2, H2O)
  • storage temp.  :Sealed in dry,Room Temperature
  • solubility  :H2O: 0.1 g/mL hot, clear to very faintly turbid, colorless
  • form  :Powder
  • pka :12.69±0.70(Predicted)
  • color  :White to Off-white
  • optical activity :[α]20/D 39±2°, c = 2% in H2O
  • Water Solubility  :83 g/L (25 ºC)
  • Merck  :14,597
  • BRN  :66856
  • InChIKey :XUCIJNAGGSZNQT-SWRVSKMJSA-N
  • CAS DataBase Reference :29883-15-6(CAS DataBase Reference)
  • EWG's Food Scores :1
  • FDA UNII :214UUQ9N0H
  • NCI Dictionary of Cancer Terms :amygdalin; laetrile
  • NCI Drug Dictionary :laetrile
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P264-P270-P301+P312+P330-P501-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Amygdalin Price More Price(16)
  • Brand: Sigma-Aldrich
  • Product number: 10050
  • Product name : Amygdalin
  • Purity: BioXtra, ≥97.0% (HPLC)
  • Packaging: 5g
  • Price: $88.5
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 10050
  • Product name : Amygdalin
  • Purity: BioXtra, ≥97.0% (HPLC)
  • Packaging: 25g
  • Price: $339
  • Updated: 2021/03/22
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  • Brand: TCI Chemical
  • Product number: A0443
  • Product name : Amygdalin
  • Purity: >97.0%(HPLC)
  • Packaging: 1g
  • Price: $24
  • Updated: 2021/03/22
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  • Brand: Alfa Aesar
  • Product number: J61472
  • Product name : D-Amygdalin, 98%
  • Purity: 
  • Packaging: 1g
  • Price: $29.6
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Alfa Aesar
  • Product number: J61472
  • Product name : D-Amygdalin, 98%
  • Purity: 
  • Packaging: 5g
  • Price: $76.5
  • Updated: 2021/03/22
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Amygdalin Chemical Properties,Usage,Production

  • Uses and Synthetic Methods of Amygdalin Amygdalin is a β-cyano-glycoside in the bitter almond that is bound to cyano (CN), which releases free cyano groups after eating the bitter almond, so that the food is poisoned. Amygdalin is a product of the metabolism of phenylalanine in the bitter almond. Amygdalin has β-glucosidase and amygdalinase (oxynitrilase): the former catalyzed amygdalin into two molecules of glucose and one molecule of amygdalenone through hydrolysis; the later catalyzes mandelonitrile into almond nitrile cyanide (HCN) and benzaldehyde through hydrolysis. Amygdalin exists in seeds, such as almonds.
    Many plant root cells contain glycosides, with no toxic effect when in sugar type. Glycosides hydrolysis produce toxic substances leading to cell death. Mandelic glycosides contained in peach root is a glycoside. Amylose hydrolysis produce two kinds of plant toxins-hydrogen cyanide and benzaldehyde. Peeling root lesion formation and necrosis occurred in the vicinity of the stabbed nematode but not in contact zone; in addition, in vitro tests have proved that the pratylenchus penetrans can make amygdalin hydrolysis.
    As a cyanide containing glucoside, it can be used as a substrate for such as maltase, almond casein and β-glucosidase identification, differentiation and characterization.
  • Category Toxic substances
  • Toxicity classification Highly toxic
  • Acute toxicity Acute toxicity Oral-Rat LD50: 522 mg/kg; Oral-mouse LD50: 443 mg/kg
  • Flammability Hazardous properties Combustible; producing toxic nitrogen oxides when heated.
  • Storage and transportation Ventilation, low temperature, drying
  • Fire extinguishing agent Dry powder, foam, sand, carbon dioxide
  • Chemical Properties WHITE FINE CRYSTALLINE POWDER
  • Uses antiinflammatory, experimental antineoplastic
  • Definition ChEBI: An amygdalin in which the stereocentre on the cyanohydrin function has R-configuration.
  • World Health Organization (WHO) Laetrile, which consists mainly of amydgalin, a glycoside extracted from the kernels of apricots, peaches and other fruits, has been available for over 30 years in preparations purporting to be beneficial in the treatment of cancer. Although there is no evidence that these are efficacious, preparations continued to be widely used and, until the late 1970s, they were considered to be harmless. However, oral dosage forms, which may be broken down in the gut to hydrogen cyanide, have subsequently been shown to be potentially lethal. This has resulted in restrictive regulatory measures in several countries.
  • Safety Profile Human poison by ingestion(infant data). Poison experimentally by ingestion. Anexperimental teratogen. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.
  • Purification Methods D-Amygdalin recrystallises from water as the trihydrate, or from EtOH. It is present in bitter almonds. [Smith Chem Ber 64 1115 1931, Beilstein 17/8 V 188.]
Amygdalin Preparation Products And Raw materials
Raw materials
Preparation Products
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29883-15-6, AmygdalinRelated Search:
  • (r)-alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)benzeneaceto
  • (r)-alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)benzeneacetonit
  • (r)-oxy)
  • (r)-y)
  • amygdaloside
  • benzeneacetonitrile,alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)
  • benzeneacetonitrile,alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)ox
  • Amygdalin 29883-15-6
  • 2-(hydroxymethyl)-6-[[3,4,5-trihydroxy-6-(methoxymethyl)-2-oxanyl]methoxymethyl]oxane-3,4,5-triol
  • D(-)-Amygdalin hydrate,95%
  • [(6-O-Hexopyranosylhexopyranosyl)-oxy](phenyl)-acetonitrile
  • AMYGDALIN
  • 6-O-BETA-D-GLUCOSIDO-BETA-D-GLUCOSIDE
  • d(-)-mandelonitrile-beta-d-gentiobioside
  • mandelonitrile-beta-gentiobioside
  • nsc-15780
  • rile
  • BENZENEACETONITRILE-[(6-O-BETA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSYL)OXY]-, (R)-
  • D(-)-AMYGDALIN
  • D-AMYGDALIN
  • D-AMYGDALIN HYDRATE
  • D-MANDELONITRILE 6-O-BETA-D-GLUCOSIDO-BETA-D-GLUCOSIDE
  • D-MANDELONITRILE 6-O-BETA-D-GLUCOSIDO-BETA-D-GLUCOSIDE D-MANDELONITRILE BETA-GENTIOBIOSIDE
  • D-MANDELONITRILE-BETA-D-GLUCOSIDO-6-BETA-D-GLUCOSIDE
  • D-MANDELONITRILE-BETA-GENTIOBIOSIDE
  • GLUCOPRUNASIN
  • LAETRILE
  • MANDELONITRILE GENTIOBIOSIDE
  • Amygdalin,D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside, D-Mandelonitrile-β-gentiobioside, Laetrile
  • D-Amygdalin, 98+%
  • D-Amygdalin,D-Mandelonitrile β-gentiobioside, D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside, D-Mandelonitrile-β-gentiobioside, Amygdalin, Laetrile
  • D-Mandelonitrile-β-gentiobioside ,98%
  • Benzeneacetonitrile,alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyr
  • AMygdalin(VitaMin B17
  • AMygdaloside (disaccharide)
  • Nitrilosides
  • (R)-2-phenyl-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)Methyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile
  • AMygdalin /VB17/Laetrile
  • AMygdalin /VB17/Laetril
  • Bitter AlMond extract
  • D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside
  • D-Mandelonitrile-β-gentiobioside
  • Mygdalin
  • D-AMYGDALIN FROM APRICOT KERNELS
  • AMYGDALIN: BENZENEACETONITRILE,-[(6-O--D-GLUCOPYRANOSYL--D-GLUCOPYRANOSYL)OXY]-, (R)-
  • D-Amygdalin (1.12428)
  • D-Amygdalinhydrate,96%
  • Benzeneacetonitrile, .alpha.-(6-O-.beta.-D-glucopyranosyl-.beta.-D-glucopyranosyl)oxy-, (.alpha.R)-
  • d-mandelonitrile-á-d-glucosido-6-á-d-glucoside
  • vitamin b17
  • D-Mandelonitrile-b-gentiobioside
  • AMYGDALIN(RG)
  • D,L-AMYGDALIN
  • (2R)-2-Phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyacetonitrile
  • (R)-Amygdalin
  • (R)-Amygdaloside
  • (R)-Laenitrile
  • AMYGDALIN BIOXTRA, >= 97.0% (HPLC)