11-Hydroxycanthin-6-one

Uses

11-Hydroxycanthin-6-one, a canthin-6-one (HY-N3536) alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].

Definition

ChEBI: Amalorin is an organic heterotetracyclic compound and an alkaloid.

References

[1] Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3. DOI:10.1055/s-2006-962656
[2] Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5(1):17-22. PMID:20184012