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Seratrodast

Seratrodast Structure
Seratrodast
  • CAS No.112665-43-7
  • Chemical Name:Seratrodast
  • CBNumber:CB8284400
  • Molecular Formula:C22H26O4
  • Formula Weight:354.44
  • MOL File:112665-43-7.mol
Seratrodast Property
  • Melting point: :118-120°C
  • Boiling point: :522.3±49.0 °C(Predicted)
  • Density  :1.140±0.06 g/cm3(Predicted)
  • storage temp.  :Store at +4°C
  • form  :Yellow-orange solid.
  • pka :4.76±0.10(Predicted)
  • Merck  :14,8459
  • CAS DataBase Reference :112665-43-7(CAS DataBase Reference)
  • FDA UNII :4U58JM421N
Safety
  • RTECS  :DA1600050
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H361
  • Precautionary statements P201-P202-P280-P308+P313-P405-P501
Seratrodast Price More Price(5)
  • Brand: TCI Chemical
  • Product number: S0943
  • Product name : Seratrodast
  • Purity: >98.0%(HPLC)(T)
  • Packaging: 1g
  • Price: $749
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: S0943
  • Product name : Seratrodast
  • Purity: >98.0%(HPLC)(T)
  • Packaging: 100mg
  • Price: $126
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 9002014
  • Product name : Seratrodast
  • Purity: ≥98%
  • Packaging: 10mg
  • Price: $35
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 9002014
  • Product name : Seratrodast
  • Purity: ≥98%
  • Packaging: 25mg
  • Price: $105
  • Updated: 2020/06/24
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 9002014
  • Product name : Seratrodast
  • Purity: ≥98%
  • Packaging: 50mg
  • Price: $193
  • Updated: 2020/06/24
  • Buy: Buy

Seratrodast Chemical Properties,Usage,Production

  • Description Seratrodast, a novel benzoquinone derivative, is the first thromboxane A2 (TxA2) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA2, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA2 mimic and by a variety of spasmogenic prostanoids including PGF, PGD2 and 9α,11β-PGF2. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer.
  • Chemical Properties Pale Orange Solid
  • Originator Takeda (Japan)
  • Uses antibacterial
  • Uses Thromboxane A2-receptor antagonist. Antiasthmatic
  • brand name Bronica
  • Biological Activity Thromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs.
Seratrodast Preparation Products And Raw materials
Raw materials
Preparation Products
Global(156)Suppliers
  • Supplier:
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112665-43-7, SeratrodastRelated Search:
  • 50MG/200MG/1G
  • benzeneheptanoic acid, -(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-
  • (+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoicacid
  • aa-2414
  • beta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-bezeneheptanoicaci
  • Seratrodast(AA-2414,ABT-001)
  • AA-2414;SERETRA;AA2414;AA 2414
  • Seretra
  • Seratrodast AA 2414
  • CS-324
  • 5-(2,4,5-trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benzeneheptanoic acid
  • 7-(3,5,6-trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid
  • 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid
  • Bronica
  • Abbott 73001
  • Bronic
  • (±)-ζ-2,4,5-Trimethyl-3,6-dioxo-1,4-cyclohexadien-1-y1)benzeneheptanoic acid
  • 7-(3,6-diketo-2,4,5-trimethyl-cyclohexa-1,4-dien-1-yl)-7-phenyl-enanthic acid
  • 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dien-1-yl)heptanoic acid
  • 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)heptanoic acid
  • Serabenast
  • Seratrodast
  • Seratrodast &gt
  • ABT-001
  • 112665-43-7
  • C22H26O4
  • ZAGAM
  • API
  • Heterocyclic Compounds
  • Intermediates & Fine Chemicals
  • Pharmaceuticals