MPEG16-NH2
- Product NameMPEG16-NH2
- CAS907577-50-8
- CBNumberCB82720252
- MFC33H69NO16
- MW735.9
- MDL NumberMFCD31656924
- MOL File907577-50-8.mol
Chemical Properties
Boiling point | 699.1±50.0 °C(Predicted) |
Density | 1.084±0.06 g/cm3(Predicted) |
pka | 8.74±0.10(Predicted) |
MPEG16-NH2 Chemical Properties,Usage,Production
Biological Activity
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Preparation Products And Raw materials
MPEG16-NH2 Suppliers
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