Uses
Bioactive sphingolipids with an attached label or tag are useful tools for localisation, binding and metabolism studies and as assay substrates. Used in an assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes.
Biological Activity
Biotin Sphingosineplays a vital role in identifying sphingosine interaction with acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A).
References
[1] JANE L. ROBERTS . An assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes[J]. Analytical biochemistry, 2004, 331 1: Pages 122-129. DOI:
10.1016/j.ab.2004.03.030
