Uses
Reactant for synthesis of:
Nicotinic acid receptor agonists for treatment of dyslipidemia
1-Alkylcyclanols with side chain functions
Benzhydrylamides for pharmacochemical studies
Reactant for:
Elimination reactions
Hydrogenation of esters to alcohols
General Description
Ethyl 1-piperidineacetate (Piperidin-1-ylacetic acid ethyl ester) is an α-amino acid ethyl ester derivative. Thermal decomposition of ethyl 1-piperidineacetate in gas phase has been studied by
ab initio theoretical methods. The kinetics of gas-phase decomposition of ethyl 1-piperidineacetate to the corresponding α-amino acid derivative and ethylene over the temperature range of 360-430°C and pressure range of 26-86Torr has been investigated. Alkylation reaction of ethyl 1-piperidineacetate with ethyl bromoacetate in absolute ethanol has been reported to obey second order kinetics.