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Sodium thiosulfate pentahydrate

Sodium thiosulfate pentahydrate Structure
Sodium thiosulfate pentahydrate
  • CAS No.10102-17-7
  • Chemical Name:Sodium thiosulfate pentahydrate
  • CBNumber:CB8108182
  • Molecular Formula:H10Na2O8S2
  • Formula Weight:248.18
  • MOL File:10102-17-7.mol
Sodium thiosulfate pentahydrate Property
  • Melting point: :48.5 °C
  • Boiling point: :100 C
  • Density  :1.01 g/mL at 25 °C
  • storage temp.  :Store at +5°C to +30°C.
  • solubility  :H2O: 1 M at 20 °C, clear, colorless
  • form  :Solid
  • color  :White tranparent
  • Specific Gravity :1.729
  • Odor :Odorless
  • PH Range :6 - 8.5
  • PH :6.0-7.5 (100g/l, H2O, 20℃)
  • Water Solubility  :680 g/L (20 ºC)
  • Merck  :14,8694
  • Stability: :Stable. Incompatible with strong acids, iodine, mercury.
  • InChIKey :AKHNMLFCWUSKQB-UHFFFAOYSA-L
  • Substances Added to Food (formerly EAFUS) :SODIUM THIOSULFATE
  • SCOGS (Select Committee on GRAS Substances) :Sodium thiosulfate
  • CAS DataBase Reference :10102-17-7(CAS DataBase Reference)
  • EPA Substance Registry System :Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate (10102-17-7)
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :24/25-37/39-36-26
  • WGK Germany  :1
  • RTECS  :WE6660000
  • F  :10
  • TSCA  :Yes
  • HS Code  :28323000
  • Toxicity :LD50 orally in Rabbit: > 5000 mg/kg
  • NFPA 704:
    0
    1 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Sodium thiosulfate pentahydrate Price More Price(40)
  • Brand: Sigma-Aldrich
  • Product number: 1.09147
  • Product name : Sodium thiosulfate solution
  • Purity: c(Na?S?O? 5 H?O) = 0.1 mol/l (0.1 N) Titripur? Reag. Ph Eur,Reag. USP
  • Packaging: 1 L
  • Price: $22.29
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 13479
  • Product name : Sodium thiosulfate pentahydrate
  • Purity: puriss., meets analytical specification of Ph. Eur., BP, USP, 99-100.5%
  • Packaging: 500g-r
  • Price: $49.9
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: HT1005
  • Product name : Sodium thiosulfate solution
  • Purity: 2?g/dL in deionized water
  • Packaging: 100 mL
  • Price: $55.4
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1.06516
  • Product name : Sodium thiosulfate pentahydrate
  • Purity: for analysis EMSURE? ACS,ISO,Reag. Ph Eur
  • Packaging: 500 g
  • Price: $59.57
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1.06514
  • Product name : Sodium thiosulfate pentahydrate
  • Purity: cryst., EMPROVE? ESSENTIAL Ph Eur,BP,USP
  • Packaging: 0.75 kg
  • Price: $37.1
  • Updated: 2021/03/22
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Sodium thiosulfate pentahydrate Chemical Properties,Usage,Production

  • Chemical Properties translucent crystals or white powder
  • Chemical Properties Sodium thiosulfate occurs as odorless and colorless crystals, a crystalline powder or granules. It is efflorescent in dry air and deliquescent in moist air.
  • Uses Titrimetry.
  • Production Methods On an industrial scale, sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.
  • brand name Sulfactol (Sterling Winthrop).
  • Pharmaceutical Applications Sodium thiosulfate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations). It has also been used for its antifungal properties and as a reagent in analytical chemistry.
  • Safety Sodium thiosulfate is used in ophthalmic, intravenous, and oral pharmaceutical preparations. Apart from osmotic disturbances, sodium thiosulfate is relatively nontoxic. It is moderately toxic by the subcutaneous route and mildly irritating to respiratory tract and skin. Large oral doses have a cathartic action.
    LD50 (IP, mouse) 5.6 g/kg
    LD50 (IV, mouse) 2.4 g/kg
  • storage Sodium thiosulfate decomposes on heating. The bulk powder should be stored in a cool place, and the container should be kept tightly closed in a dry and well-ventilated place. It should not be stored near acids.
  • Purification Methods Crystallise it from EtOH/H2O solutions or from water (0.3mL/g) below 60o by cooling to 0o, and dry it at 35o over P2O5 under vacuum. [Foerster & Mommsen Chem Ber 57 258 1924.] This salt is used as a secondary standard in volumetric analysis [Kilpatrick J Am Chem Soc 45 2132 1923], and is used as “Hypo” in photography [Hargreaves & Dunningham J Soc Chem Ind 42 147T 1923.]
  • Incompatibilities Sodium thiosulfate is incompatible with iodine, with acids, and with lead, mercury, and silver salts. It may reduce the activity of some preservatives, including bronopol, phenylmercuric salts, and thimerosal.
  • Regulatory Status GRAS listed. Included in the FDA Inactive Ingredients Database (IV solutions; ophthalmic solutions and suspensions; oral capsules, solutions, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium thiosulfate pentahydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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