N-DECANOYLGLYCINE

Uses

N-Decanoylglycine, is from a Fatty acid glycolate group, acting as potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase.

Definition

ChEBI: N-decanoylglycine is an N-acylglycine with an acyl group that is decanoyl. It has a role as a metabolite. It is a N-acylglycine, a fatty amide and a secondary carboxamide. It is functionally related to a decanoic acid. It is a conjugate acid of a N-decanoylglycinate.

Biochem/physiol Actions

Decanoylglycine is an acylglycine with C-10 fatty acid group as the acyl moiety. Acylglycines possess a common amidoacetic acid moiety and are normally minor metabolites of fatty acids. Elevated levels of certain acylglycines appear in the urine and blood of patients with various fatty acid oxidation disorders. They are normally produced through the action of glycine N-acyltransferase which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine <-> CoA + N-acylglycine.