Chemical Properties
Yellow Oil
Chemical Properties
N-nitrosodi-N-propylamine is a yellow liquid.
Uses
Research chemical; impurity
in herbicides treflan, isopropalin, and trifluralin;
contaminant in wastewater from chemical
factories and production of cheese and
brandy and other liquors. N-nitrosamines are
frequently produced during rubber processing
and may be airborne in the workplace.
Uses
N-Nitrosodi-n-propylamine is used in small quantities in laboratory research. It has no known commercial use (IARC 1978, ATSDR 1989, HSDB 2009).
Definition
ChEBI: N-Nitrosodi-n-propylamine is a nitroso compound.
General Description
Clear to pale yellow liquid.
Reactivity Profile
N-NITROSODI-N-PROPYLAMINE is a nitrated amine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: Toxic.
Fire Hazard
Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.
Safety Profile
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic data. Moderately
toxic by ingestion and subcutaneous routes.
An experimental teratogen. Human
mutation data reported. When heated to
decomposition it emits toxic fumes of NOx.
See also NITROSAMINES.
Potential Exposure
N-nitrosodi-N-propylamine is used in
the manufacture of plastics, resins, rubber, and synthetic
textiles. There is no evidence that N-nitrosodi-N-propylamine
exists naturally in soil, air, food, or water. Small
quantities of N-nitrosodi-N-propylamine are inadvertently
produced during some manufacturing processes; as an
impurity in some commercially available dinitroaniline
based weed killers, and during the manufacture of some
rubber products. However, according to Sax, some similar
N-nitroso compounds are formed in the environment and
absorbed from precursors in food, water, or air; from
tobacco; and from naturally occurring compounds.
Carcinogenicity
N-Nitrosodi-n-propylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Environmental Fate
Chemical/Physical. N-Nitroso-n-propylamine will not hydrolyze because it does not contain a
hydrolyzable functional group (Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities were
24, 13, 7.4, and 4.0 mg/g, respectively (Dobbs and Cohen, 1980).
Shipping
UN3082 Environmentally hazardous substances,
liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous
hazardous material, Technical Name Required
Incompatibilities
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Sensitive to UV light.
Waste Disposal
N-Nitrosodi-N-propylamine
may be destroyed by high temperature incineration in an
incinerator equipped with an nitrogen oxide scrubber.
Chemical treatment methods may also be used to destroy
N-nitrosodi-N-propylamine. These methods involve
(a) denitrosation by reaction with 3% hydrobromic acid in
glacial acetic acid; (b) oxidation by reaction with potassium
permanganate-sulfuric acid; or (c) extraction of the nitrosamine
from the waste using dichloromethane and subsequent
reaction with triethyloxonium tetrafluoroborate (TOEF).
Consult with environmental regulatory agencies for guidance
on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform
with EPA regulations governing storage, transportation,
treatment, and waste disposal.
