Chemical Properties
white to beige powder and/or chunks
Uses
2,6-Diaminopimelic acid (2,6-DAP) can be used as a building block in the synthesis of tripeptides , and γ-glutamyldiaminopimelic acid derivatives.
Uses
Mixture of LL-, DD- and meso-isomers
Uses
2,6-Diaminopimelic acid is used as a constituent of proteoglycans. It is used as a component of bacterial cell wall.
Definition
ChEBI: The amino dicarboxylic acid that is heptanedioic acid with amino aubstituents at C-2 and C-6.
General Description
2,6-Diaminopimelic acid is produced in bacteria and is a component of cell wall. It is also synthesized by higher plants.
Biochem/physiol Actions
2,6-Diaminopimelic acid is essential for microbial metabolism and is a potential marker for quantification of microbial proteins. It is a sensitive and reliable marker and is majorly quantified using gradient high-performance liquid chromatography (HPLC).
Purification Methods
Crystallise the acid from H2O or aqueous EtOH. Also purify it by dissolving it in hot H2O and adding 5volumes of EtOH, filter after 12hours at -10o. The acid has been recrystallised from 35% aqueous EtOH [Wade et al. J Am Chem Soc 79 648, 651 1957]. [Beilstein 4 IV 3081.]
