(20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol

Description

This alkaloid occurs in Buxus sernpervirens var. bullatus and forms colourless needles from Me2CO. It is dextrorotatory with a specific rotation of [α]_D²⁵ + 20° (c 0.59, MeOH) and gives an ultraviolet spectrum in EtOH with absorption maxima at 236, 246, 255 and 273 nm. Treatment with methyl iodide yields buxaminol A.

References

Bauerova, Paulik, Collect. Czech. Chern. Cornrnun., 40, 3055 (1975)