Description
2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent commonly used in chemical and experimental research as a reagent for the phosphorylation of alcohols and heteroatoms for the formation of glycosyl donors and ligands, and in analytical studies of derivatised lignin samples. It is also used as a catalyst in CuO/TiO2 catalysed lignin oxidation studies.
Chemical Properties
2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is an organic reagent in the physical state of a solid. Molecular weight: 182.59, Density: 1.149 g/cm
3, Boiling point: 81.5-82° C (lit.) at 13 mmHg, Flash point: 113 °C, Refractive index: n20/D 1.471 (lit.), Store at 10°C-25°C, keep dry, under inert gas nitrogen.
Uses
2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (TMDP) can be used:
- As a reagent for the phosphitylation of alcohols and heteroatomic nucleophiles, resulting in the formation of useful glycosyl donors and ligands.
- As a phosphitylation reagent to derivatize lignin samples for 31P NMR analysis.
