DIOCTADECYLAMINE

Uses

Dioctadecylamine (DODA) is suitable reagent used in the synthesis of the following:

• Dioctadecylamine-BCN (bicyclo[6.1.0]nonyne) conjugate.
• Lipid derivatives of bisethylnorspermine (BSP).
• Functional VP (N-vinylpyrrolidone ) polymers.

It may be used in the following studies:

• As a reactant in the synthesis of 4,4′-azobis(4-cyano-N,N-dioctadecyl)pentanamide (DODA-501) by reacting with disuccinimidyl 4,4′-azobis(4-cyanovalerate).
• As a reagent in the synthesis of dioctadecyl heptapeptides.
• As a phase transfer and stabilizer agent for gold nanoparticles (AuNPs) in non-polar solvent.

General Description

Dioctadecylamine (DODA), a secondary amine, is a fatty amine derivative. Its biodegradation potential has been assessed. It has been observed that in aqueous medium DODA self organizes into plate like structures. Its partial charge distribution as a function of its conformation has been analyzed. The phase diagram of dioctadecylamine Langmuir monolayers has been determined and investigations show it does not form a monolayer above pH 3.9. DODA has been utilized in forming liposomes, cationic lipids or lipid chelating agents.