Chemical Properties
White crystalline powder
Uses
Gly-gly-leu is an oligopeptide, and also functions as a plant growth regulator.
Definition
ChEBI: Gly-Gly-Leu is a tripeptide composed of glycine, glycine and L-leucine residues joined in sequence. It has a role as a metabolite.
Synthesis
Glycylglycyl-L-leucine was prepared in 98% yield by hydrogenolysis of the protected tripeptide and crystallization of the product from aqueous ethanol. This matarial had [α]
24D -28.4° (c, 2 in water), reported [α]
20D -28. l° (c, 2.53 in water), [α]
26D -28.0°, and [α]19
D -29.9° (c, 2 in water)[1].
References
[1] Beechham A, et al. Residue rotations of L-leucine in the Di-, Tri-, Tetra-, and Penta-peptides of L-leucine and Glycine containing one L-leucyl residue. Australian Journal of Chemistry, 1967; 20: 1983 - 1989.
