Chemical Properties
White to Off-White Solid
Uses
SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor with anti-inflammatory properties. SC-58125 blocks edema and hyperalgesia without causing gastric mucosal damage. SC-58125 also displays anti
tumor activity.
Definition
ChEBI: A member of the class of pyrazoles that is 1H-pyrazole substituted by a 4-fluorophenyl group at position 5, a 4-(methylsulfonyl)phenyl group at position 1 and a trifluoromethyl group at position 3. A selective cyclooxygenase 2 inhibitor
it exhibits anticancer property.
Biological Activity
Selective cyclooxygenase 2 (COX-2) inhibitor (IC 50 values are 0.04 and >100 μ M for COX-2 and COX-1 respectively). Anti-inflammatory; blocks edema and hyperalgesia in vivo following an inflammatory insult, without causing gastric mucosal damage. Also displays antitumor activity.
![1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE Structure](https://www.chemicalbook.com/CAS/GIF/162054-19-5.gif)
