Chemical Properties
Stannous fluoride is a white crystalline solid with a bitter, salty taste.
Chemical Properties
white crystals or powder
Uses
Dental caries prophylactic.
Uses
Stannous fluoride (SnF2) is used as a toothpaste additive to help prevent tooth decay.
Uses
Tin(II) fluoride is used in the prevention of dental caries. It is an active ingredient in toothpastes.
Definition
ChEBI: Stannous fluoride is an inorganic fluoride salt.
General Description
White crystalline solid. Sinks and mixes with water.
Air & Water Reactions
Water soluble.
Reactivity Profile
Tin(II) fluoride, a strong reducing agent, is incompatible with oxidizers. Avoid contact with acids - HF fumes may be produced [USCG, 1999].
Hazard
Toxic by ingestion, strong irritant to skin
and tissue.
Health Hazard
EYES: Severe irritation - corrosive, irreversible. SKIN: Corrosive on abraded skin, no effect on intact skin.
Flammability and Explosibility
Not classified
reaction suitability
core: tin
reagent type: catalyst
Biological Activity
The wild type human brahma-related gene 1 (Brg1) encodes a protein of 1,647 amino acids th at contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription regulation. BRG1 is an essential component of the SWI/SNF chromatin remodeling complexes and implicated in multiple functions through its interaction with different proteins, including the tumor suppressor protein pRb, serine-threonine kinase LKB1, and other transcription factors. Although Brg1 is involved in chromatin remodeling as a complex with other SWI/SNF proteins, purified BRG1 itself is capable of remodeling mono-nucleosomes and nucleosomal arrays in vitro. Mutations of Brg1 have been found in multiple tumor cell lines.
Safety Profile
Poison by ingestion and
intraperitoneal routes. Questionable
carcinogen. Mutation data reported. When
heated to decomposition it emits toxic
fumes of F-. See also TIN COMPOUNDS.
Potential Exposure
Stannous fluoride is used in dental caries (tooth decay); as an ingredient of cavity-preventing toothpastes.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2923 Corrosive solids, toxic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, 6.1Poisonous material, Technical Name Required
Incompatibilities
A strong reducing agent. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Reacts with acids, forming hydrogen fluoride fumes. Reacts violently with chlorine and metal nitrates. Reacts with metals releasing flammable hydrogen gas.
