Description
The mono-methyl terephthalate is a kind of phthalate ester. It can be obtained during the hydrolytical transformation process of dimethyl terephthalate (DMT) by some microbes such as Rhodococcus rubber and Pasteurella multocida. It is also the intermediate during the manufacturing of dimethyl terephthalate, terephthalic acid and some other derivatives. As the ester form of terephthalate, it is widely used for the manufacturing of plastics, paints, synthetic fibers and polyester.
References
Schoengen, Anton, Georg Schreiber, and Heinz Schroeder. U.S. Patent No. 4,302,595. 24 Nov. 1981.
Li, Jiaxi, Ji-Dong Gu, and Li Pan. International Biodeterioration & Biodegradation 55.3 (2005): 223-232.
Li, Jiaxi, Ji-Dong Gu, and Jun-hua Yao. International Biodeterioration & Biodegradation 56.3 (2005): 158-165.
Uses
mono-Methyl Terephthalate is used in the synthesis of Hepatits C antiviral activity. Also used in the design and preparation of benzamide derivatives as BRAFV600E inhibitors, which if mutated, can influence malignancies and melanomas.
