Uses
2-Methyl-1-propenyl Trifluoromethanesulfonate is used as a precursor to dimethylvinylidene carbene, 2-methyl-1-propenyl ethers, isopropylidenecyclopropanes, isopropylidenecyclopropenes, 3-isopropylindazoles, and 2-methyl-1-propenyltriphenylphosphonium triflates.
Synthesis Reference(s)
1.Stang, P. J.; Treptow, W. S 1980, 283.
Synthesis
2-Methyl-1-propenyl Trifluoromethanesulfonate is synthesized in a single step from 2-methylpropionaldehyde, Trifluoromethanesulfonic Anhydride, and a hindered pyridine in 1,2-dichloroethane at reflux (eq 1). Distillation gives the product in 45% yield.
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