Propargyl-PEG5-amine

Description

Propargyl-PEG5-amine is a propargyl linker that is commonly used as a Click Chemistry reagent for copper-catalyzed reactions with azides. The amine moiety reacts with carboxylic acids, activated NHS esters and other carbonyl compounds. The PEG spacer helps improve the water solubility of the molecule in aqueous media.

Biological Activity

Propargyl-PEG5-amine is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PROTAC linker belonging to the PEG class and can be used to synthesize a series of PROTAC molecules.

in vitro

target

Non-cleavable < span>

PEGs